Nanomaterials as Analytical Tools for Genosensors

Sensors

Khalid M. Abu-Salah¹  Salman A. Alrokyan¹  Muhammad Naziruddin Khan¹ 

[1]King Abdullah Institute for Nanotechnology, King Saud University, Riyadh-11451, P.O Box-2454, Saudi Arabia

关键词: nanomaterials;    oligonucleotides;    ZnO;    carbon nanotubes;    conducting polymers;   

DOI  :  10.3390/s100100963

来源: mdpi

【 摘 要 】

Nanomaterials are being increasingly used for the development of electrochemical DNA biosensors, due to the unique electrocatalytic properties found in nanoscale materials. They offer excellent prospects for interfacing biological recognition events with electronic signal transduction and for designing a new generation of bioelectronic devices exhibiting novel functions. In particular, nanomaterials such as noble metal nanoparticles (Au, Pt), carbon nanotubes (CNTs), magnetic nanoparticles, quantum dots and metal oxide nanoparticles have been actively investigated for their applications in DNA biosensors, which have become a new interdisciplinary frontier between biological detection and material science. In this article, we address some of the main advances in this field over the past few years, discussing the issues and challenges with the aim of stimulating a broader interest in developing nanomaterial-based biosensors and improving their applications in disease diagnosis and food safety examination.

【 授权许可】

CC BY   
©2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.