Surface Engineering and Patterning Using Parylene for Biological Applications

Materials

Christine P. Tan¹ 

[1] Department of Biomedical Engineering, Cornell University, Ithaca, New York, NY 14853, USA; E-Mail:

关键词: parylene;    micropatterning;    surface modification;    [2.2]paracyclophane;    biomaterial;    bioactive;    biomolecular;    nanobiotechnology;    microarray;    microfluidic;   

DOI  :  10.3390/ma3031803

来源: mdpi

【 摘 要 】

Parylene is a family of chemically vapour deposited polymer with material properties that are attractive for biomedicine and nanobiotechnology. Chemically inert parylene “peel-off” stencils have been demonstrated for micropatterning biomolecular arrays with high uniformity, precise spatial control down to nanoscale resolution. Such micropatterned surfaces are beneficial in engineering biosensors and biological microenvironments. A variety of substituted precursors enables direct coating of functionalised parylenes onto biomedical implants and microfluidics, providing a convenient method for designing biocompatible and bioactive surfaces. This article will review the emerging role and applications of parylene as a biomaterial for surface chemical modification and provide a future outlook.

【 授权许可】

CC BY   
© 2010 by the authors; licensee MDPI, Basel, Switzerland.