Marine Drugs | |
Cyanobacterial Cyclopeptides as Lead Compounds to Novel Targeted Cancer Drugs | |
Ioannis Sainis2  Demosthenes Fokas1  Katerina Vareli2  Andreas G. Tzakos2  Valentinos Kounnis3  | |
[1] Department of Materials Science and Engineering, University of Ioannina, Greece; E-Mail:;Human Cancer Biobank Center, University of Ioannina, Greece; E-Mails:;School of Medicine, University of Ioannina, Greece; E-Mail: | |
关键词: microcystin; cyanobacteria; cyanotoxins; cancer; targeted-therapy; OATP; membrane transporters; | |
DOI : 10.3390/md8030629 | |
来源: mdpi | |
【 摘 要 】
Cyanobacterial cyclopeptides, including microcystins and nodularins, are considered a health hazard to humans due to the possible toxic effects of high consumption. From a pharmacological standpoint, microcystins are stable hydrophilic cyclic heptapeptides with a potential to cause cellular damage following uptake
【 授权许可】
CC BY
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland
【 预 览 】
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