Current Research and Development of Chemotherapeutic Agents for Melanoma

Cancers

Kyaw Minn Hsan¹  Chun-Chieh Chen¹ 

关键词: cutaneous malignant melanoma;    metastasis;    chemotherapeutic drugs;    herbal medicines;    phytoagents;   

DOI  :  10.3390/cancers2020397

来源: mdpi

【 摘 要 】

Cutaneous malignant melanoma is the most lethal form of skin cancer and an increasingly common disease worldwide. It remains one of the most treatment-refractory malignancies. The current treatment options for patients with metastatic melanoma are limited and in most cases non-curative. This review focuses on conventional chemotherapeutic drugs for melanoma treatment, by a single or combinational agent approach, but also summarizes some potential novel phytoagents discovered from dietary vegetables or traditional herbal medicines as alternative options or future medicine for melanoma prevention. We explore the mode of actions of these natural phytoagents against metastatic melanoma.

【 授权许可】

CC BY   
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.