Molecules | |
A Facile One-pot Synthesis of 1-Arylpyrazolo[3,4-d]Pyrimidin- 4-ones | |
Xiaohong Zhang1  Qiulian Lin1  | |
[1] 1Oujiang College, Wenzhou Universtity, Wenzhou 325035, China 2College of Chemistry and Materials Engineering, Wenzhou Universtity, Wenzhou 325035, China | |
关键词: POCl3; one-pot; RCOOH; pyrazolo[3; 4-d]pyrimidine; | |
DOI : 10.3390/molecules15053079 | |
来源: mdpi | |
【 摘 要 】
One pot synthesis of 1-arylpyrazolo[3,4-d]pyrimidin-4-ones by the reaction of 5-amino-N-substituted-1H-pyrazole-4-carbonitrile with different lower aliphatic acids in the presence of POCl3has been developed. The structures of all the title compounds have been confirmed by IR, 1H-NMR, 13C-NMR, and elemental analyses. Moreover, the structures of one of these compounds, 2c, was confirmed by single-crystal X-ray diffraction.
【 授权许可】
CC BY
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
【 预 览 】
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RO202003190053837ZK.pdf | 188KB | download |