The Role of Non-Steroidal Anti-Inflammatory Drugs in Renal Colic

Pharmaceuticals

Kim Davenport¹ 

关键词: renal colic;    ureteric stone;    Non-steroidal anti-inflammatory drugs;   

DOI  :  10.3390/ph3051304

来源: mdpi

【 摘 要 】

NSAIDs provide optimal analgesia in renal colic due to the reduction in glomerular filtration and renal pelvic pressure, ureteric peristalsis and ureteric oedema. Prevention of glomerular afferent arteriolar vasodilatation renders these patients at risk of renal impairment. NSAIDs have the additional benefit of reducing the number of new colic episodes and preventing subsequent readmission to hospital. Despite recent work promoting the use of pharmacological agents to improve stone passage rates, NSAIDs do not appear to reduce the time to stone passage or increase the likelihood of stone passage in renal colic.

【 授权许可】

CC BY   
© 2010 by the authors; licensee MDPI, Basel, Switzerland.