Fluorescent Chemosensors for Toxic Organophosphorus Pesticides: A Review

Sensors

Sherine O. Obare²  Chandrima De²  Wen Guo²  Tajay L. Haywood²  Tova A. Samuels²  Clara P. Adams²  Noah O. Masika²  Desmond H. Murray¹  Ginger A. Anderson²  Keith Campbell¹ 

[1] Department of Chemistry and Biochemistry, Andrews University, Berrien Springs, MI 49104, USA; E-Mails:;Department of Chemistry, Western Michigan University, Kalamazoo, MI 49008, USA; E-Mails:

关键词: organophosphorus compounds;    fluorescent chemosensors;    pollutants;    dual modes of signal transduction;   

DOI  :  10.3390/s100707018

来源: mdpi

【 摘 要 】

Many organophosphorus (OP) based compounds are highly toxic and powerful inhibitors of cholinesterases that generate serious environmental and human health concerns. Organothiophosphates with a thiophosphoryl (P=S) functional group constitute a broad class of these widely used pesticides. They are related to the more reactive phosphoryl (P=O) organophosphates, which include very lethal nerve agents and chemical warfare agents, such as, VX, Soman and Sarin. Unfortunately, widespread and frequent commercial use of OP-based compounds in agricultural lands has resulted in their presence as residues in crops, livestock, and poultry products and also led to their migration into aquifers. Thus, the design of new sensors with improved analyte selectivity and sensitivity is of paramount importance in this area. Herein, we review recent advances in the development of fluorescent chemosensors for toxic OP pesticides and related compounds. We also discuss challenges and progress towards the design of future chemosensors with dual modes for signal transduction.

【 授权许可】

CC BY   
© 2010 by the authors licensee MDPI, Basel, Switzerland.