期刊论文详细信息
Molecules | |
Synthesis and Reactivity of [1,2,4]Triazolo-annelated Quinazolines | |
关键词: triazolo[1; 5-a]quinazolines; thionation; alkylation; chlorination; tetracyclic systems; | |
DOI : 10.3390/molecules15107016 | |
来源: mdpi | |
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【 摘 要 】
This paper reports the synthesis of phenyl-substituted 2-alkoxy(methylsulfanyl)-1,2,4-triazolo[1,5-a]quinazolines starting from N-cyanoimidocarbonates and substituted hydrazinobenzoic acids as building blocks. Thionation or chlorination of the inherent lactam moiety in the target compounds followed by treatment with multifunctional nucleophiles provided access to a variety of derivatives.【 授权许可】
CC BY
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
【 预 览 】
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