Malaria Prophylaxis: A Comprehensive Review

Pharmaceuticals

Francesco Castelli¹  Silvia Odolini¹  Beatrice Autino¹  Emanuele Foca¹ 

[1] Institute for Infectious and Tropical Diseases, University of Brescia, Piazza Spedali Civili, 1 - 25123–Brescia, Italy

关键词: malaria;    prophylaxis;    traveller;   

DOI  :  10.3390/ph3103212

来源: mdpi

【 摘 要 】

The flow of international travellers to and from malaria-endemic areas, especially Africa, has increased in recent years. Apart from the very high morbidity and mortality burden imposed on malaria-endemic areas, imported malaria is the main cause of fever possibly causing severe disease and death in travellers coming from tropical and subtropical areas, particularly Sub-Saharan Africa. The importance of behavioural preventive measures (bed nets, repellents, etc.), adequate chemoprophylaxis and, in selected circumstances, stand-by emergency treatment may not be overemphasized. However, no prophylactic regimen may offer complete protection. Expert advice is needed to tailor prophylactic advice according to traveller (age, baseline clinical conditions, etc.) and travel (destination, season, etc.) characteristics in order to reduce malaria risk.

【 授权许可】

CC BY   
© 2010 by the authors; licensee MDPI, Basel, Switzerland.