Recent N-Atom Containing Compounds from Indo-Pacific Invertebrates

Marine Drugs

Yoel Kashman¹  Ashgan Bishara¹ 

[1] School of Chemistry, Tel Aviv University, Tel Aviv University, Ramat Aviv 69978, Israel

关键词: heterocycles;    Fascaplysinopsis sp.;    marine invertebrates;    nitrogenous macrolide;    leukemia cells;   

DOI  :  10.3390/md8112810

来源: mdpi

【 摘 要 】

A large variety of unique N-atom containing compounds (alkaloids) without terrestrial counterparts, have been isolated from marine invertebrates, mainly sponges and ascidians. Many of these compounds display interesting biological activities. In this report we present studies on nitrogenous compounds, isolated by our group during the last few years, from Indo-Pacific sponges, one ascidian and one gorgonian. The major part of the review deals with metabolites from the Madagascar sponge Fascaplysinopsis sp., namely, four groups of secondary metabolites, the salarins, tulearins, taumycins and tausalarins.

【 授权许可】

CC BY   
© 2010 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland