Epidemiology of Skin Cancer: Role of Some Environmental Factors

Cancers

Gabriella Fabbrocini¹  Maria Triassi²  Maria Chiara Mauriello¹  Guglielma Torre²  Maria Carmela Annunziata¹  Valerio De Vita¹  Francesco Pastore¹  Vincenza D𠆚rco¹ 

[1] Department of Systematic Pathology, Division of Dermatology, University of Naples Federico II, Naples, Italy; E-Mails:;Department of Preventive Medical Sciences, Division of Hygiene, University of Naples Federico II Naples, Italy; E-Mails:

关键词: skin cancer epidemiology;    environmental factors;    UV radiation;    arsenic;    climate change;   

DOI  :  10.3390/cancers2041980

来源: mdpi

【 摘 要 】

The incidence rate of melanoma and non-melanoma skin cancer entities is dramatically increasing worldwide. Exposure to UVB radiation is known to induce basal and squamous cell skin cancer in a dose-dependent way and the depletion of stratospheric ozone has implications for increases in biologically damaging solar UVB radiation reaching the earth’s surface. In humans, arsenic is known to cause cancer of the skin, as well as cancer of the lung, bladder, liver, and kidney. Exposure to high levels of arsenic in drinking water has been recognized in some regions of the world. SCC and BCC (squamous and basal cell carcinoma) have been reported to be associated with ingestion of arsenic alone or in combination with other risk factors. The impact of changes in ambient temperature will influence people’s behavior and the time they spend outdoors. Higher temperatures accompanying climate change may lead, among many other effects, to increasing incidence of skin cancer.

【 授权许可】

CC BY   
© 2010 by the authors; licensee MDPI, Basel, Switzerland.