Synthesis and Biological Activity of Novel Phenyltriazolinone Derivatives

Molecules

Qiongyou Wu¹  Guodong Wang¹  Shaowei Huang¹  Long Lin¹ 

[1] Key Laboratory of Pesticide and Chemical Biology of Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, Hubei, China

关键词: phenyltriazolinones;    strobilurin;    herbicidal activity;    protoporphyrinogen oxidase;   

DOI  :  10.3390/molecules15129024

来源: mdpi

【 摘 要 】

Phenyltriazolinones are one of the most important classes of herbicides targeting the protoporphyrinogen oxidase enzyme. A series of triazolinone derivatives containing a strobilurin pharmacophore were designed and synthesized with the aim of discovering new phenyltriazolinone analogues with high activity. The herbicidal activity of the synthesized compounds was assayed and some of the test compounds displayed moderate herbicidal activity at 150 g ai/ha.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.