In vitro Biocompatibility of New Silver(I) Coordination Compound Coated-Surfaces for Dental Implant Applications

Materials

Priscilla S. Brunetto¹  Tünde Vig Slenters¹ 

[1] id="af1-materials-04-00355">University of Fribourg, Department of Chemistry, Chemin du Musée 9, CH-1700 Fribourg, Switzerla

关键词: silver;    cytotoxicity;    biocompatibility;   

DOI  :  10.3390/ma4020355

来源: mdpi

【 摘 要 】

Biofilm formation on implant materials causes a common problem: resistance to aggressive pharmacological agents as well as host defenses. Therefore, to reduce bacterial adhesion to implant surfaces we propose to use silver(I) coordination networks as it is known that silver is the most powerful antimicrobial inorganic agent. As a model surface, self-assembled monolayers (SAMs) on gold Au(111) was used to permit permanent attachment of our silver(I) coordination networks. The surface coatings showed typical nano-structured surfaces with a good biocompatibility for soft-tissue integration with fibroblast cells.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.