Preparation of Silver- and Zinc-Doped Mullite-Based Ceramics Showing Anti-Bacterial Biofilm Properties

Molecules

Suhair Saleh¹  Mutasem O. Taha¹  Randa N. Haddadin¹  Duá Marzooqa¹ 

[1] ¹Department of Pharmaceutical Sciences and Pharmaceutics, Applied Science University, Amman, Jordan

关键词: mullite;    silver;    zinc;    bacterial attachment;    Pseudomonas aeruginosa;   

DOI  :  10.3390/molecules16042862

来源: mdpi

【 摘 要 】

Zinc- and silver-doped mullite ceramic discs were prepared and tested as potentially resistant materials against bacterial adhesion and biofilm formation. Elemental analysis and X-ray diffraction studies showed that zinc ions were incorporated in the structural framework of the mullite, while silver ions remained outside the mullite crystal lattice, which allowed their slow (0.02 ppm/24 hours) leaching into the surrounding aqueous environment. In agreement with this behavior, silver-doped mullite showed potent resistance against surface attachment of Pseudomonas aeruginosa, while on the other hand, zinc-doped mullite failed to stop bacterial attachment.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.