Molecules | |
Copper(I)-Catalyzed [ 3+ 2] Cycloaddition of 3-Azidoquinoline-2,4(1H,3H)-diones with Terminal Alkynes | |
Stanislav Kafka1  Sylvia Hauke1  Arjana Salcinovic1  Otto Soidinsalo1  Damijana Urankar1  | |
[1] 1Department of Chemistry, Faculty of Technology, Tomas Bata University in Zlin, Zlin 76272, Czech Republic | |
关键词: cycloaddition; azides; quinoline-2; 4(1H; 3H)-diones; terminal alkynes; 1; 2; 3-triazoles; | |
DOI : 10.3390/molecules16054070 | |
来源: mdpi | |
【 摘 要 】
3-Azidoquinoline-2,4(1H,3H)-diones 1, which are readily available from 4-hydroxyquinolin-2(1H)-ones 4 via 3-chloroquinoline-2,4(1H,3H)-diones 5, afford, in copper(I)-catalyzed [3 + 2] cycloaddition reaction with terminal acetylenes, 1,4-disubstituted 1,2,3-triazoles 3 in moderate to excellent yields. The structures of compounds 3 were confirmed by 1H and 13C-NMR spectroscopy, combustion analyses and mass spectrometry.
【 授权许可】
CC BY
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
【 预 览 】
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