International Journal of Molecular Sciences | |
Global Transcriptomic Profiling Using Small Volumes of Whole Blood: A Cost-Effective Method for Translational Genomic Biomarker Identification in Small Animals | |
Meagan M. Fricano1  Amy C. Ditewig1  Paul M. Jung2  Michael J. Liguori2  Eric A. G. Blomme2  | |
[1] Global Pharmaceutical Research and Development, Abbott Laboratories, 100 Abbott Park Road, Abbott Park, Il 60064, USA; | |
关键词: blood; biomarker; inflammation; transcriptomics; | |
DOI : 10.3390/ijms12042502 | |
来源: mdpi | |
【 摘 要 】
Blood is an ideal tissue for the identification of novel genomic biomarkers for toxicity or efficacy. However, using blood for transcriptomic profiling presents significant technical challenges due to the transcriptomic changes induced by
【 授权许可】
CC BY
© 2011 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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