Effects of Oral Glucosamine Hydrochloride Administration on Plasma Free Amino Acid Concentrations in Dogs

Marine Drugs

Kazuo Azuma²  Tomohiro Osaki²  Takeshi Tsuka²  Tomohiro Imagawa²  Yoshiharu Okamoto²  Yoshimori Takamori¹ 

[1] Koyo Chemical Co. Ltd., 2-11-1 Koraku, Bunkyoku, Tokyo 112-0004, Japan;Department of Veterinary Clinical Medicine, School of Veterinary Medicine, Tottori University, 4-101 Koyama-minami, Tottori 680-8553, Japan; E-Mails:

关键词: glucosamine hydrochloride;    N-acetyl-d-glucosamine;    amino acid;    dog;   

DOI  :  10.3390/md9050712

来源: mdpi

【 摘 要 】

We examined the effects of oral glucosamine hydrochloride (GlcN), N-acetyl-d-glucosamine (GlcNAc) and d-glucose (Glc) administration on plasma total free amino acid (PFAA) concentrations in dogs. The PFAA concentrations increased in the control group and the GlcNAc group at one hour after feeding, and each amino acid concentration increased. On the other hand, in the GlcN group and the Glc group PFAA concentrations decreased at one hour after feeding. A significant decrease in amino acid concentration was observed for glutamate, glycine and alanine. Our results suggest the existence of differences in PFAA dynamics after oral administration of GlcN and GlcNAc in dogs.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.