Behavior of Phenols and Phenoxyacids on a Bisphenol-A Imprinted Polymer. Application for Selective Solid-Phase Extraction from Water and Urine Samples

International Journal of Molecular Sciences

Eliseo Herrero-Hernández²  Rita Carabias-Martínez¹ 

[1] Department of Analytical Chemistry, Nutrition and Food Sciences, University of Salamanca, 37008 Salamanca, Spain; E-Mail:;Institute of Natural Resources and Agrobiology (IRNASA-CSIC), 37008 Salamanca, Spain; E-Mail:

关键词: molecularly imprinted polymer;    precipitation polymerisation;    Scatchard analysis;    bisphenol-A;    phenolic compounds;    phenoxyacid herbicides;   

DOI  :  10.3390/ijms12053322

来源: mdpi

【 摘 要 】

A molecularly imprinted polymer (MIP), obtained by precipitation polymerisation with 4-vinylpyridine as the functional monomer, ethylene glycol dimethacrylate as cross-linker, and bisphenol-A (BPA) as template, was prepared. The binding site configuration of the BPA-MIP was examined using Scatchard analysis. Moreover, the behaviour of the BPA-MIP for the extraction of several phenolic compounds (bisphenol-A, bisphenol-F, 4-nitrophenol, 3-methyl-4-nitrophenol) and phenoxyacid herbicides such as 2,4-D, 2,4,5-T and 2,4,5-TP has been studied in organic and aqueous media in the presence of other pesticides in common use. It was possible to carry out the selective preconcentration of the target analytes from the organic medium with recoveries of higher than 70%. In an aqueous medium, hydrophobic interactions were found to exert a remarkably non-specific contribution to the overall binding process. Several parameters affecting the extraction efficiency of the BPA-MIP were evaluated to achieve the selective preconcentration of phenols and phenoxyacids from aqueous samples. The possibility of using the BPA-MIP as a selective sorbent to preconcentrate these compounds from other samples such as urine and river water was also explored.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.