Monasnicotinates A–D, Four New Pyridine Alkaloids from the Fungal Strain Monascus pilosus BCRC 38093

Molecules

Ming-Der Wu¹  Ming-Jen Cheng¹  Yi-Jen Yech¹  Yen-Lin Chen¹  Kai-Ping Chen¹  Ih-Sheng Chen¹  Ping-Hsun Yang¹ 

[1] ¹Bioresource Collection and Research Center (BCRC), Food Industry Research and Development Institute (FIRDI), Hsinchu 300, Taiwan ²School of Pharmacy, College of Pharmacy, Kaohsiung Medical University (KMU), Kaohsiung 807, Taiwan ^†These authors contributed equally to this work.

关键词: Monascus pilosus BCRC 38093;    pyridine derivatives;    NO production;   

DOI  :  10.3390/molecules16064719

来源: mdpi

【 摘 要 】

Four new pyridine derivatives, monasnicotinates A–D (1–4) were isolated from the red yeast rice of Monascus pilosus BCRC 38093. Their structures were elucidated on the basis of physicochemical evidence, in-depth NMR spectroscopic analysis, and high-resolution mass spectrometry. Their inhibitory effects on NO production was also evaluated.

【 授权许可】

CC BY   
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