Microwave Assisted Suzuki-Miyaura and Ullmann Type Homocoupling Reactions of 2- and 3-Halopyridines Using a Pd(OAc)2/Benzimidazolium Salt and Base Catalyst System

Molecules

Ülkü Yılmaz³  Selma Deniz¹  Hasan Küçükbay² 

[1] Department of Elementary Education, Faculty of Education, Hakkari University, Hakkari 30000, Turkey; E-Mail:;Department of Chemistry, Faculty of Science, İnönü University, Malatya 44280, Turkey;Battalgazi Vocational School, İnönü University, Battalgazi, Malatya 44210, Turkey; E-Mail:

关键词: Suzuki-Miyaura reaction;    homocoupling;    N-heterocyclic carbene;    microwave;    pyridine derivatives;   

DOI  :  10.3390/molecules18043712

来源: mdpi

【 摘 要 】

A number of novel benzimidazole derivatives 1–4 were synthesized and the catalytic activity of these compounds in a catalytic system consisting of a benzimidazolium salt/Pd(OAc)₂/K₂CO₃ were investigated in the Suzuki-Miyaura and Ullmann type homocoupling reactions under microwave irradiation. We obtained both cross coupling and homocoupling products of pyridine and some side products such as dimethylaminopyridine and unsubstituted pyridine.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.