Suzuki-Miyaura Reactions Catalyzed by C2-Symmetric Pd-Multi-Dentate N-Heterocyclic Carbene Complexes

Molecules

Lan Jiang¹  Fengjun Shan²  Zhengning Li² 

[1] State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China;College of Environmental and Chemical Engineering, Dalian University, Dalian 116622, China;

关键词: imidazolium salt;    N-heterocyclic carbene;    palladium;    Suzuki-Miyaura coupling;    catalysis;   

DOI  :  10.3390/molecules171012121

来源: mdpi

【 摘 要 】

Suzuki-Miyaura coupling reactions are promoted by Pd complexes ligated with C₂-symmetric multi-dentate N-heterocyclic carbenes derived in situ from Pd(OAc)₂ and imidazolium salts. Good to excellent yields were obtained for aryl bromides as substrates. Turnover numbers of up to 10⁵ could be achieved with 5 × 10⁻⁴ mol% of Pd(OAc)₂/1 × 10⁻³ mol% NHC precatalyst in 24 h.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.