Expeditious Entry to Novel 2-Methylene-2,3-dihydrofuro[3,2-c] chromen-2-ones from 6-Chloro-4-hydroxychromen-2-one and Propargylic Alcohols

Molecules

Noel Nebra¹  Alba E. Díaz-Álvarez¹  Josefina Díez¹ 

[1] Departamento de Química Orgánica e Inorgánica, IUQOEM-CSIC, Facultad de Química, Universidad de Oviedo, E-33071 Oviedo, Spain

关键词: chromen-2-ones;    furochromen-2-ones;    propargylic alcohols;    ruthenium catalysts;    propargylation;    cycloisomerization;   

DOI  :  10.3390/molecules16086470

来源: mdpi

【 摘 要 】

A catalytic system consisting of the ruthenium(II) complex [Ru(η³-2-C₃H₄Me)(CO)(dppf)][SbF₆] (dppf = 1,1’-bis(diphenylphosphino)ferrocene) and trifluoroacetic acid has been used to promote the coupling of secondary propargylic alcohols with 6-chloro-4-hydroxychromen-2-one. The reactions afforded unusual 2-methylene-2,3-dihydrofuro[3,2-c]chromen-2-ones in good yields.

【 授权许可】

CC BY   
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