Assessment of Tamarindus indica Extracts for Antibacterial Activity

International Journal of Molecular Sciences

Uchechukwu U. Nwodo¹  Grace E. Obiiyeke²  Vincent N. Chigor¹ 

[1] Applied and Environmental Microbiology Research Group (AEMREG), Department of Biochemistry and Microbiology, University of Fort Hare, Private Bag X1314, Alice 5700, South Africa; E-Mails:;Department of Botany, Delta State University, Abraka, 330106, Delta State, Nigeria; E-Mail:

关键词: Tamarind;    Tamarindus indica;    extracts;    antibacterial activity;   

DOI  :  10.3390/ijms12106385

来源: mdpi

【 摘 要 】

Ethanolic and aqueous (hot and cold) extracts of the fruit pulp, stem bark and leaves of Tamarindus indica were evaluated for antibacterial activity, in vitro, against 13 Gram negative and 5 Gram positive bacterial strains using agar well diffusion and macro broth dilution techniques, simultaneously. The fruit pulp extracts exhibited a wide spectrum of activity; the cold water extract against 95.5% of the test bacterial strains; and the hot water and ethanolic extracts against 90.9% and 86.4%, respectively. In contrast the cold water extract of the leaves and stem bark, each was active against 16.7%; while the ethanolic extract of each was active against 75% of the test strains. The minimum inhibitory concentrations (MIC) ranged from 7.81 mg/mL against Bacillus subtilis ATCC 6051 to 31.25 mg/mL against Escherichia coli ATCC 11775; and the minimum bactericidal concentration (MBC) ranged from 125 mg/mL against Pseudomonas aeruginosa ATCC 10145 to 250 mg/mL against Bacillus subtilis ATCC 6051.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.