Synthesis of [(4-Chloro-5H-1,2,3-dithiazol-5-ylidene)amino]azines

Molecules

Panayiotis A. Koutentis¹  Maria Koyioni¹ 

[1] Department of Chemistry, University of Cyprus, P.O. Box 20537, 1678 Nicosia, Cyprus

关键词: heterocycle;    Appel salt;    1;    2;    3-dithiazoles;    condensation;    azine;   

DOI  :  10.3390/molecules16118992

来源: mdpi

【 摘 要 】

The reactions of 2-, 3- and 4-aminopyridines with 4,5-dichloro-1,2,3-dithiazol-ium chloride (Appel salt) 4 to give N-(4-chloro-5H-1,2,3-dithiazol-5-ylidene)pyridin-X-amines 1a (X = 2), 1g (X = 3) and 1k (X = 4) were optimized with respect to base, temperature and reaction time. Based on these conditions a total of thirteen [(dithiazol-ylidene)amino]azines 1a-m were prepared and fully characterized.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.