Comparative Study Using Different Infrared Zones of the Solventless Activation of Organic Reactions

International Journal of Molecular Sciences

Mar໚ Olivia Noguez Córdova¹  Carlos I. Flores Ramírez¹  Benjamín Velasco Bejarano¹  Gabriel A. Arroyo Razo¹  Francisco J. Pérez Flores³  Vladimir Carranza Tellez² 

[1] Department of Chemistry, Faculty of Superior Studies Cuautitlan, Field 1, Autonomous National University of Mexico, Av. May 1st s/n, Z. C. 54740, Cuautitlan Izcalli, State of Mexico, Mexico; E-Mails:;Mass Spectrometry Laboratory, Center of Chemistry, Institute of Sciences, Benemérita University of Puebla, Z. C. 72570, Puebla, Mexico; E-Mail:;Mass Spectrometry Laboratory, Institute of Chemistry, Autonomous National University of Mexico, Outer City, University City, Z. C. 04510, Coyoacan, D. F., Mexico; E-Mail:

关键词: solventless;    comparative study;    infrared irradiation;    green approach;   

DOI  :  10.3390/ijms12128575

来源: mdpi

【 摘 要 】

In this work, the results of a study comparing the use of irradiation from different regions of the infrared spectrum for the promotion of several organic reactions, are presented and discussed. This use of eco-conditions provides a green approach to chemical synthesis. A set of ten different organic reactions were evaluated, including the Knoevenagel, Hantzsch, Biginelli and Meldrum reactions. It is important to highlight the use of a commercial device that produces infrared irradiation in the near infrared region and its distribution by convection providing heating uniformity, significantly reducing reaction times, achieving good yields and proceeding in the absence of solvent. It is also worth noting that a variety of different reactions may be performed at the same time. Finally, the products obtained were identified using TLC, together with corresponding MS-data, complementarily in comparison of NMR ¹H and ¹³C data with literature information.

【 授权许可】

CC BY   
© 2011 by the authors; licensee MDPI, Basel, Switzerland.