Probiotic Encapsulation Technology: From Microencapsulation to Release into the Gut

Pharmaceutics

Gildas K. Gbassi¹ 

[1]Laboratoire de Conception et Application de Molécules Bioactives (UMR-7199), Faculté de Pharmacie, UdS-CNRS, 74 Route du Rhin, 67401 Illkirch-Graffenstaden, France

关键词: biomaterials;    microencapsulation;    probiotics;    protective device;    artificial media;    cells release;   

DOI  :  10.3390/pharmaceutics4010149

来源: mdpi

【 摘 要 】

Probiotic encapsulation technology (PET) has the potential to protect microorgansisms and to deliver them into the gut. Because of the promising preclinical and clinical results, probiotics have been incorporated into a range of products. However, there are still many challenges to overcome with respect to the microencapsulation process and the conditions prevailing in the gut. This paper reviews the methodological approach of probiotics encapsulation including biomaterials selection, choice of appropriate technology, in vitro release studies of encapsulated probiotics, and highlights the challenges to be overcome in this area.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.