Biosensors | |
Fabrication of Biocompatible, Vibrational Magnetoelastic Materials for Controlling Cellular Adhesion | |
Hal R. Holmes1  Ee Lim Tan1  Keat Ghee Ong2  | |
[1] Department of Biomedical Engineering, Michigan Technological University, Houghton, MI 49931, USA; | |
关键词: magnetoelastic (ME) material; Parylene-C; biocompatibility; plasma etching; cellular adhesion; | |
DOI : 10.3390/bios2010057 | |
来源: mdpi | |
【 摘 要 】
This paper describes the functionalization of magnetoelastic (ME) materials with Parylene-C coating to improve the surface reactivity to cellular response. Previous study has demonstrated that vibrating ME materials were capable of modulating cellular adhesion when activated by an externally applied AC magnetic field. However, since ME materials are not inherently biocompatible, surface modifications are needed for their implementation in biological settings. Here, the long-term stability of the ME material in an aqueous and biological environment is achieved by chemical-vapor deposition of a conformal Parylene-C layer, and further functionalized by methods of oxygen plasma etching and protein adsorption.
【 授权许可】
CC BY
© 2012 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190045900ZK.pdf | 665KB | download |