Molecular Mechanisms of Transcription Activation by Juvenile Hormone: A Critical Role for bHLH-PAS and Nuclear Receptor Proteins

Insects

Travis J. Bernardo¹ 

[1] Department of Biology, Fordham University, Bronx, NY 10458, USA; E-Mail:

关键词: Drosophila melanogaster;    juvenile hormone;    nuclear receptor;    bHLH-PAS;    methoprene-tolerant;    germ cell-expressed;   

DOI  :  10.3390/insects3010324

来源: mdpi

【 摘 要 】

Juvenile hormone (JH) is responsible for controlling many biological processes. In several insect species JH has been implicated as a key regulator of developmental timing, preventing the premature onset of metamorphosis during larval growth periods. However, the molecular basis of JH action is not well-understood. In this review, we highlight recent advances which demonstrate the importance of transcription factors from the bHLH-PAS and nuclear receptor families in mediating the response to JH.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.