Nucleic Acid Based Fluorinated Derivatives: New Tools for Biomedical Applications

Applied Sciences

Christel Dolain¹  Amit Patwa¹  Guilhem Godeau¹ 

[1] Université de Bordeaux, Bordeaux F-33076, France;

关键词: fluorocarbon;    amphiphile;    lipids;    nucleoside;    oligonucleotides;   

DOI  :  10.3390/app2020245

来源: mdpi

【 摘 要 】

Nucleic acid-based fluorinated derivatives, e.g., nucleosides or oligonucleotides connected to highly fluorinated chains or labeled with one or more fluorine atoms, have been investigated recently due to their high potential for biomedical applications. This review deals with recent works on nucleoside and oligonucleotide fluorocarbon amphiphiles as well as with properties and applications of fluorine-labeled oligonucleotide analogues.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.