Toxins | |
Cytotoxicity and Glycan-Binding Properties of an 18 kDa Lectin Isolated from the Marine Sponge |
|
Ryo Matsumoto1  Yuki Fujii1  Sarkar M. A. Kawsar1  Robert A. Kanaly1  Hidetaro Yasumitsu1  Yasuhiro Koide1  Imtiaj Hasan1  Chihiro Iwahara1  Yukiko Ogawa3  Chang Hun Im4  Shigeki Sugawara4  Masahiro Hosono4  Kazuo Nitta4  Jiharu Hamako2  Taei Matsui2  | |
[1] Laboratory of Glycobiology and Marine Biochemistry, Department of Genome System Science, Graduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan;Department of Biology, Fujita Health University, Toyoake, Aichi 470-1192, Japan;Divisions of Functional Morphology and Microbiology, Department of Pharmacy, Faculty of Pharmaceutical Science, Nagasaki International University, 2825-7 Huis Ten Bosch, Sasebo, Nagasaki 859-3298, Japan;Division of Cell Recognition Study, Institute of Molecular Biomembrane and Glycobiology, Tohoku Pharmaceutical University, 4-4-1 Komatsusima, Aoba-ku, Sendai 981-8558, Japan; | |
关键词:
cytotoxicity;
frontal affinity chromatography technology;
glycoprotein;
Japanese black sponge ( |
|
DOI : 10.3390/toxins4050323 | |
来源: mdpi | |
【 摘 要 】
A divalent cation-independent lectin—HOL-18, with cytotoxic activity against leukemia cells, was purified from a demosponge,
【 授权许可】
CC BY
© 2012 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202003190044730ZK.pdf | 795KB | download |