Molecules | |
Two New Diterpenoids from the Buds of Wikstroemia chamaedaphne | |
Jieru Guo1  Jinwen Zhang1  Penghua Shu1  Lingmei Kong1  Xincai Hao1  Yongbo Xue1  Zengwei Luo1  Yan Li1  Gao Li1  Guangmin Yao1  | |
[1] 1Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation, School of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China | |
关键词: Wikstroemia chamaedaphne; diterpenoids; lignans; cytotoxicity; | |
DOI : 10.3390/molecules17066424 | |
来源: mdpi | |
【 摘 要 】
Two new diterpenoids, wikstroelide Q (1) and prostratin Q (5), together with three known diterpenoids, pimelea factors P2 (2), P3 (3), and prostratin (4), and five known lignans, (+)-epipioresinol (6), (+)-isolariciresinol (7), (−)-lariciresinol (8), (+)-epi-sesaminone (9), and prestegane B (10), were isolated from the buds of Wikstroemia chamaedaphne Meissn. Their structures were elucidated by a combination of spectroscopic analyses. Compounds 1–10 were evaluated for their cytotoxicities against HL-60, SMMC-7721, A549, MCF-7, SW480, and BEAS-2B cell lines in vitro.
【 授权许可】
CC BY
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
【 预 览 】
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RO202003190043899ZK.pdf | 320KB | download |