A Portable and Power-Free Microfluidic Device for Rapid and Sensitive Lead (Pb2+) Detection

Sensors

Chunhui Fan¹  Shijiang He³  Gang Liu²  Lianhui Wang¹ 

[1] Laboratory of Advanced Materials, Fudan University, 2205 Songhu Road, Shanghai 200438, China; E-Mail:;Shanghai Institute of Measurement and Testing Technology, Shanghai 201203, China; E-Mail:;Laboratory of Physical Biology, Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China; E-Mail:

关键词: gold nanoparticles;    Pb²⁺;    11-mercaptoundecanoic acid;    microfluidic chip;   

DOI  :  10.3390/s120709467

来源: mdpi

【 摘 要 】

A portable and power-free microfluidic device was designed for rapid and sensitive detection of lead (Pb²⁺). 11-mercaptoundecanoic acid (MUA)-functionalized gold nanoparticles (MUA-AuNPs) aggregated in the presence of Pb²⁺ for the chelation mechanism. When we performed this analysis on a polydimethylsiloxane (PDMS) microfluidic chip, the aggregations deposited onto the surface of chip and formed dark lines along the laminar flows in the zigzag microchannels. This visual result can be observed by the naked eye through a microscope or just a drop of water as a magnifier. Ten μM Pb²⁺ was successfully detected.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.