1-(1H-Benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one

Molbank

Mohd Rashid¹  Asif Husain¹  Ravinesh Mishra¹  Niyaz Ahmed¹ 

[1] ¹Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi 110062, India

关键词: Benzimidazole;    oxadiazole;    trichloroacetic acid;   

DOI  :  10.3390/M766

来源: mdpi

【 摘 要 】

The title compound, 1-(1H-benzimidazol-2-yl)-3-[5-(trichloromethyl)-1,3,4-oxadiazol-2-yl]propan-1-one (2) was synthesized successfully from 4-(1H-benzimidazol-2-yl)-4-oxobutanehydrazide (1) under microwave irradiation in good yield by reacting with trichloroacetic acid, and the structure of title compound was confirmed on the basis of IR, ¹H-NMR, ¹³C-NMR, MS and CHN analyses results.

【 授权许可】

CC BY   
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