A Systematic Study on the Self-Assembly Behaviour of Multi Component Fmoc-Amino Acid-Poly(oxazoline) Systems

Polymers

Pier-Francesco Caponi¹ 

[1] Laboratory of Organic and Macromolecular Chemistry (IOMC), Friedrich-Schiller-University Jena, Jena 07745, Germany

关键词: responsive polymers;    amino acids;    enzyme responsive materials;   

DOI  :  10.3390/polym4031399

来源: mdpi

【 摘 要 】

We report a systematic study of a modular approach to create multi-component supramolecular nanostructures that can be tailored to be both enzyme and temperature responsive. Using a straightforward synthetic approach we functionalised a thermal responsive polymer, poly(2-isopropyl-2-oxazoline), with fluorenylmethoxycarbonyl-amino acids that drive the self-assembly. Depending on the properties of appended amino acids, these polymers undergo substantial morphological changes in response to the catalytic action of alkaline phosphatase.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.