International Journal of Molecular Sciences | |
Effects of Rice Bran Oil on the Intestinal Microbiota and Metabolism of Isoflavones in Adult Mice | |
Motoi Tamura1  Sachiko Hori2  Chigusa Hoshi2  | |
[1] National Food Research Institute, the National Agriculture and Food Research Organization, Tsukuba, Ibaraki 305-8642, Japan; | |
关键词: rice bran oil; equol; daidzein; mice; intestinal microbiota; | |
DOI : 10.3390/ijms130810336 | |
来源: mdpi | |
【 摘 要 】
This study examined the effects of rice bran oil (RBO) on mouse intestinal microbiota and urinary isoflavonoids. Dietary RBO affects intestinal cholesterol absorption. Intestinal microbiota seem to play an important role in isoflavone metabolism. We hypothesized that dietary RBO changes the metabolism of isoflavonoids and intestinal microbiota in mice. Male mice were randomly divided into two groups: those fed a 0.05% daidzein with 10% RBO diet (RO group) and those fed a 0.05% daidzein with 10% lard control diet (LO group) for 30 days. Urinary amounts of daidzein and dihydrodaidzein were significantly lower in the RO group than in the LO group. The ratio of equol/daidzein was significantly higher in the RO group (
【 授权许可】
CC BY
© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190042580ZK.pdf | 263KB | download |