International Journal of Molecular Sciences | |
Xylitol Affects the Intestinal Microbiota and Metabolism of Daidzein in Adult Male Mice | |
Motoi Tamura1  Chigusa Hoshi2  | |
[1] National Food Research Institute, National Agriculture and Food Research Organization, Tsukuba, Ibaraki 305-8642, Japan; | |
关键词: xylitol; equol; daidzein; mice; intestinal microbiota; | |
DOI : 10.3390/ijms141223993 | |
来源: mdpi | |
【 摘 要 】
This study examined the effects of xylitol on mouse intestinal microbiota and urinary isoflavonoids. Xylitol is classified as a sugar alcohol and used as a food additive. The intestinal microbiota seems to play an important role in isoflavone metabolism. Xylitol feeding appears to affect the gut microbiota. We hypothesized that dietary xylitol changes intestinal microbiota and, therefore, the metabolism of isoflavonoids in mice. Male mice were randomly divided into two groups: those fed a 0.05% daidzein with 5% xylitol diet (XD group) and those fed a 0.05% daidzein-containing control diet (CD group) for 28 days. Plasma total cholesterol concentrations were significantly lower in the XD group than in the CD group (
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland
【 预 览 】
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RO202003190031086ZK.pdf | 963KB | download |