A New Cubitane Diterpenoid from the Soft Coral Sinularia crassa

Molecules

Ching-Hsiao Cheng¹  Yun-Sheng Lin¹  Zhi-Hong Wen¹ 

[1] ¹Department of Neurosurgery, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Kaohsiung 833, Taiwan

关键词: diterpenes;    soft coral;    Sinularia crassa;   

DOI  :  10.3390/molecules170910072

来源: mdpi

【 摘 要 】

A new cubitane diterpenoid, crassalone A (1), was isolated from the marine soft coral Sinularia crassa. The structure was determined by extensive spectroscopic analyses. Compound 1 is not cytotoxic (IC₅₀ > 20 μg/mL) toward the four human cancer cell lines tested (HL60, MDA-MB-231, HCT-116 and DLD-1).

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.