Synthetic Approaches and Pharmacological Activity of 1,3,4-Oxadiazoles: A Review of the Literature from 2000–2012

Molecules

Cledualdo Soares de Oliveira¹  Bruno Freitas Lira¹  José Maria Barbosa-Filho¹  Jorge Gonçalo Fernandez Lorenzo¹ 

[1] ¹Department of Chemistry, Federal University of Paraíba, 58051-900 João Pessoa-PB, Brazil ²Laboratory of Pharmaceutical Technology, Federal University of Paraíba, 58051-900 João Pessoa-PB, Brazil

关键词: 1;    3;    4-oxadiazole;    synthesis methods;    pharmacological activity;    review;   

DOI  :  10.3390/molecules170910192

来源: mdpi

【 摘 要 】

This review provides readers with an overview of the main synthetic methodologies for 1,3,4-oxadiazole derivatives, and of their broad spectrum of pharmacological activities as reported over the past twelve years.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.