Biomimetic Strategies for Bone Repair and Regeneration

Journal of Functional Biomaterials

Maria G. Raucci¹  Vincenzo Guarino² 

[1] Institute of Composite and Biomedical Materials, National Research Council of Italy, P.le Tecchio 80, Naples 80125, Italy;

关键词: biomimetic coating;    bone substitute;    hydroxyapatite;    scaffold;   

DOI  :  10.3390/jfb3030688

来源: mdpi

【 摘 要 】

The osseointegration rate of implants is related to their composition and surface roughness. Implant roughness favors both bone anchoring and biomechanical stability. Osteoconductive calcium phosphate (Ca-P) coatings promote bone healing and apposition, leading to the rapid biological fixation of implants. It has been clearly shown in many publications that Ca-P coating accelerates bone formation around the implant. This review discusses two main routes for the manufacturing of polymer-based osteoconductive scaffolds for tissue engineering, namely the incorporation of bioceramic particles in the scaffold and the coating of a scaffold with a thin layer of apatite through a biomimetic process.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.