Bioactive Oleanane, Lupane and Ursane Triterpene Acid Derivatives

Molecules

Maria de L. e Silva²  Juceni P. David²  Lidércia C. R. C. Silva²  Rauldenis A. F. Santos¹  Jorge M. David¹  Luciano S. Lima³  Pedro S. Reis⁴ 

[1] Instituto de Quimica, Universidade Federal da Bahia, Rua Barão de Geremoabo, s/n, 41810-290, Salvador, BA, Brazil;Faculdade de Farmácia, Universidade Federal da Bahia, Rua Barão de Geremoabo, s/n, 41810-290, Salvador, BA, Brazil;Instituto Federal da Bahia, Campus Porto Seguro, Br 367, km 57.5 Fontana I - Porto Seguro, 45810-000, BA, Brazil;Núcleo de Pesquisa em Biodiversidade e Biotecnologia – Biotec, Universidade Federal do Piauí, Campus de Parnaíba. 64202-020, Parnaíba, PI, Brazil;

关键词: Eriope blanchetii;    Lamiaceae;    triterpene derivatives;    Artemia salina lethality;    antimicrobial activity;   

DOI  :  10.3390/molecules171012197

来源: mdpi

【 摘 要 】

Betulinic, ursolic and oleanolic acids isolated from the aerial parts of Eriope blanchetii (Lamiaceae) were subjected to different esterification reactions, yielding 12 C-3 position ester derivatives. All compounds were identified using spectroscopic techniques, such as IR, ¹H-NMR and MS. The derivatives were further investigated for their antioxidant level, Artemia salina lethality and antimicrobial activity.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.