Performance of Eudragit Coated Whispering Gallery Mode Resonator-Based Immunosensors

Sensors

Ambra Giannetti¹  Simone Berneschi¹  Francesco Baldini¹  Franco Cosi¹  Gualtiero Nunzi Conti¹ 

[1] Istituto di Fisica Applicata Nello Carrara (IFAC CNR), Via Madonna del Piano 10, 50019 Sesto Fiorentino, Firenze, Italy; E-Mails:

关键词: whispering gallery mode resonators;    immunosensors;    Eudragit;   

DOI  :  10.3390/s121114604

来源: mdpi

【 摘 要 】

Whispering gallery mode resonators (WGMR) are an efficient tool for the realization of optical biosensors. A high Q factor preservation is a crucial requirement for good biosensor performances. In this work we present an Eudragit^®L100 coated microspherical WGMR as an efficient immunosensor. The developed resonator was morphologically characterized using fluorescence microscopy. The functionalization process was tuned to preserve the high Q factor of the resonator. The protein binding assay was optically characterized in terms of specificity in buffer solution.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.