The Innate Immune-Related Genes in Catfish

International Journal of Molecular Sciences

Lei Gao²  Chongbo He²  Xueguang Liu¹  Hao Su²  Xianggang Gao²  Yunfeng Li² 

[1] Liaoning Fisheries Technology Extension Station, Shenyang 110031, China; E-Mail:;Liaoning Ocean and Fisheries Science Research Institute, Dalian 116023, China; E-Mails:

关键词: catfish;    channel catfish (Ictalurus punctatus);    innate immunity;    antimicrobial peptide;    complement;    lectin;    cytokine;    RNA-seq;    gene expression profiling;   

DOI  :  10.3390/ijms131114172

来源: mdpi

【 摘 要 】

Catfish is one of the most important aquaculture species in America (as well as in Asia and Africa). In recent years, the production of catfish has suffered massive financial losses due to pathogen spread and breakouts. Innate immunity plays a crucial role in increasing resistance to pathogenic organisms and has generated increasing interest in the past few years. This review summarizes the current understanding of innate immune-related genes in catfish, including pattern recognition receptors, antimicrobial peptides, complements, lectins, cytokines, transferrin and gene expression profiling using microarrays and next generation sequencing technologies. This review will benefit the understanding of innate immune system in catfish and further efforts in studying the innate immune-related genes in fish.

【 授权许可】

CC BY   
© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.