Cancers | |
Emerging Roles of ADAMTSs in Angiogenesis and Cancer | |
Saran Kumar1  Nithya Rao1  | |
关键词: angiogenesis; cancer; ADAMTS; metalloproteinase; proteoglycanase; tumorigenesis; metastasis; | |
DOI : 10.3390/cancers4041252 | |
来源: mdpi | |
【 摘 要 】
A Disintegrin-like And Metalloproteinase with ThromboSpondin motifs—ADAMTSs—are a multi-domain, secreted, extracellular zinc metalloproteinase family with 19 members in humans. These extracellular metalloproteinases are known to cleave a wide range of substrates in the extracellular matrix. They have been implicated in various physiological processes, such as extracellular matrix turnover, melanoblast development, interdigital web regression, blood coagulation, ovulation,
【 授权许可】
CC BY
© 2012 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190040682ZK.pdf | 1259KB | download |