One-Pot Synthesis of 2-Phenylimidazo[1,2-α]pyridines from Acetophenone, [Bmim]Br3 and 2-Aminopyridine under Solvent-Free Conditions

Molecules

Zhang-Gao Le¹  Zong-Bo Xie¹ 

[1] Department of Applied Chemistry, East China Institute of Technology, Fuzhou 344000, China

关键词: imidazo[1;    2-α]pyridine;    aromatics;    2-aminopyridine;    [Bmim]Br₃;   

DOI  :  10.3390/molecules171113368

来源: mdpi

【 摘 要 】

One-pot synthesis of 2-phenylimidazo[1,2-α]pyridines from acetophenone, [Bmim]Br₃ and 2-aminopyridine under solvent-free conditions in the presence of Na₂CO₃, gave the corresponding 2-phenylimidazo[1,2-α]pyridines in excellent yields ranging from 72% to 89%.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.