Recent Developments in the Reformatsky-Claisen Rearrangement

Molecules

Jun Ishihara¹ 

关键词: Reformatsky-Claisen rearrangement;    Reformatsky reaction;    Claisen rearrangement;    zinc;    indium;   

DOI  :  10.3390/molecules171214249

来源: mdpi

【 摘 要 】

The rearrangement of allyl α-bromoacetates with Zn dust is known as the Reformatsky-Claisen rearrangement. Whereas the Ireland-Claisen rearrangement has been widely used in the synthesis of a diverse range of natural products, the Zn-mediated Reformatsky-Claisen rearrangement has not been utilized so often. In this article, we will provide an overview of recent advances in the Reformatsky-Claisen rearrangement field, including the In-mediated Reformatsky-Claisen rearrangement we have recently developed.

【 授权许可】

CC BY   
© 2012 by the authors; licensee MDPI, Basel, Switzerland.