International Journal of Molecular Sciences | |
Inhibitor of Apoptosis Protein-Like Protein-2 as a Novel Serological Biomarker for Breast Cancer | |
Mingjun Xiang3  Wei Zhou4  Dandan Gao2  Xiansong Fang1  | |
[1] Clinical Laboratory, the First Affiliated Hospital, Gannan Medical University, Ganzhou 341000, China; E-Mail:;Institute of Medical Biology, Chinese Academy of Medical Sciences, Kunming 650118, China; E-Mail:;Department of Biochemistry & Molecular Biology, College of Medical Science, Jishou University, Jishou 416000, China;Hunan Provincial Key Laboratory for Biology and Control of Plant Diseases and Insect Pests, College of Bio-Safety Science & Technology, Hunan Agricultural University, Changsha 410128, China; E-Mail: | |
关键词: ILP-2; breast cancer; serological biomarker; | |
DOI : 10.3390/ijms131216737 | |
来源: mdpi | |
【 摘 要 】
Inhibitor of apoptosis protein-like protein-2 (ILP-2) has only been detected in the testis and in lymphoblastoid cells. Although previous studies have not reported the presence of ILP-2 in breast cancer tissues, this study indicates the presence of ILP-2 in breast cancer serum samples. To validate whether ILP-2 is a novel serological biomarker for breast cancer, we conducted two-dimensional gel electrophoresis (2DE) and matrix-assisted laser desorption/ionization-time of flight mass spectrometry analysis on 400 breast cancer serum samples and 40 non-cancer serum samples (
【 授权许可】
CC BY
© 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202003190039893ZK.pdf | 510KB | download |