International Journal of Molecular Sciences | |
Antitumor Effects of Rapamycin in Pancreatic Cancer Cells by Inducing Apoptosis and Autophagy | |
Zhi-Jun Dai1  Jie Gao3  Xiao-Bin Ma2  Hua-Feng Kang2  Bao-Feng Wang2  Wang-Feng Lu2  Shuai Lin2  Xi-Jing Wang2  | |
[1] Department of Oncology, the Second Affiliated Hospital, Medical School of Xi’an Jiaotong University, Xi’an 710004, China; E-Mails:;Department of Nephrology, the Second Affiliated Hospital, Medical School of Xi’an Jiaotong University, Xi’an 710004, China; E-Mail: | |
关键词: pancreatic carcinoma; rapamycin; mTOR; anti-tumor; apoptosis; autophagy; | |
DOI : 10.3390/ijms14010273 | |
来源: mdpi | |
【 摘 要 】
Rapamycin (Rapa), an inhibitor of mammalian target of Rapamycin (mTOR), is an immunosuppressive agent that has anti-proliferative effects on some tumors. This study aims to investigate the effects of Rapa suppressing proliferation of pancreatic carcinoma PC-2 cells
【 授权许可】
CC BY
© 2013 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland.
【 预 览 】
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