Development and Antibacterial Activity of Cashew Gum-Based Silver Nanoparticles

International Journal of Molecular Sciences

Patrick V. Quelemes¹  Felipe B. Araruna¹  Bruna E. F. de Faria⁵  Selma A. S. Kuckelhaus³  Durcilene A. da Silva¹  Ronaldo Z. Mendon๺⁴  Carla Eiras¹  Maria José dos S. Soares² 

[1] Biotec—Biodiversity and Biotechnology Research Center, Federal University of Piauí, Parnaíba, PI 64202020, Brazil; E-Mails:;Department of Veterinary Morphophysiology, Federal University of Piauí, Teresina, PI 64049550, Brazil; E-Mail:;Laboratory of Cellular Immunology, School of Medicine, University of Brasília, Brasília, DF 70910900, Brazil; E-Mail:;Laboratory of Parasitology, Butantan Institute, 05504900, São Paulo, SP, Brazil; E-Mail:;Laboratory of Forensic Ridgeology, Institute of Civil Identification of Police, II/PCDF, 70610200 DF, Brazil; E-Mail:

关键词: silver nanoparticles;    cashew gum;    antibacterial activity;    cytotoxicity;   

DOI  :  10.3390/ijms14034969

来源: mdpi

【 摘 要 】

The present study describes the development of a green synthesis of silver nanoparticles reduced and stabilized by exuded gum from Anacardium occidentale L. and evaluates in vitro their antibacterial and cytotoxic activities. Characterization of cashew gum-based silver nanoparticles (AgNPs) was carried out based on UV–Vis spectroscopy, transmission electron microscopy and dynamic light scattering analysis which revealed that the synthesized silver nanoparticles were spherical in shape, measuring about 4 nm in size with a uniform dispersal. AgNPs presented antibacterial activity, especially against Gram-negative bacteria, in concentrations where no significant cytotoxicity was observed.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.