International Journal of Molecular Sciences | |
Prognostic Value of Tumor Markers, NSE, CA125 and SCC, in Operable NSCLC Patients | |
Dangfan Yu1  Kaiqi Du2  Taifeng Liu1  | |
[1] Department of Nuclear Medicine, Zhejiang Provincial Corps Hospital, Chinese People’s Armed Police Force, Jiaxing 314000, China; E-Mail:;Department of Thoracic Surgery, Zhejiang Provincial Corps Hospital, Chinese People’s Armed Police Force, Jiaxing 314000, China; E-Mail: | |
关键词: tumor marker; CA125; NSE; SCC; lung cancer; | |
DOI : 10.3390/ijms140611145 | |
来源: mdpi | |
【 摘 要 】
The aim of this study was to investigate the prognostic value of tumor markers in operable non-small cell lung cancer (NSCLC) patients. A total of 481 NSCLC patients were enrolled in the present study. High levels of neuron-specific enolase (NSE), carbohydrate antigen 125 (CA125) and squamous cell carcinoma antigen (SCC) were detected in 306 (63.6%), 89 (18.5%) and 125 (26.0%) patients, respectively. Seventy-eight of 481 patients died of disease progression, and the median disease-free survival (DFS) and overall survival (OS) were 16.0 and 21.0 months, respectively. The three-year DFS rate was 56.7%, and the OS rate was 75.3%. For serum NSE, the three-year cumulative DFS rate for the normal and elevated group was 67.7% and 51.8% (
【 授权许可】
CC BY
© 2013 by the authors; licensee MDPI, Basel, Switzerland
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202003190035905ZK.pdf | 786KB | download |