期刊论文详细信息
Plants
In Vitro Cytotoxic Activity of Origanum vulgare L. on HCT-116 and MDA-MB-231 Cell Lines
Filip Grbović2  Milan S. Stanković2  Milena Ćurčić2  Nataᘚ Đorᄞvić1  Dragana ᘎklić2  Marina Topuzović2 
[1] Department of Biomedical Sciences, State University of Novi Pazar, Vuka Karadzica, 36300 Novi Pazar, Republic of Serbia;Department of Biology and Ecology, Faculty of Science, University of Kragujevac, Str. Radoja Domanovića No. 12, 34000 Kragujevac, Republic of Serbia
关键词: antiproliferativeactivity;    HCT-116;    MDA-MB-231;    Origanum vulgare L.;   
DOI  :  10.3390/plants2030371
来源: mdpi
PDF
【 摘 要 】

In the present investigation, we examined the cytotoxic effect of methanolic extract from Origanum vulgare on HCT-116 and MDA-MB-231 cell line in vitro. In order to determine the cytotoxic effects we used an MTT viability assay. The results showed that cell growth is significantly lower in extract treated cells compared to untreated control. The effect of inhibition of cell growth was higher in the treatment of HCT-116 cell line than in MDA-MB-231. Based on the results it is determined that O. vulgare is a significant source of biologically active substances that have cytotoxic and antiproliferative activity in vitro.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.

【 预 览 】
附件列表
Files Size Format View
RO202003190035557ZK.pdf 542KB PDF download
  文献评价指标  
  下载次数:13次 浏览次数:11次